| | Hylaluronic Acid. | Botulinum Toxin | Fat injections | Bovine based collagen | Human based collagen | Calcium Hydorxy-
Lapatite |
| Name | Restylane, Hylaform | Botox and Myobloc | Fat Injection | Zyderm, Zyplast | CosmoDerm CosmoPlast | Radiance |
| What is it? | A substance found in all living organisms | Botulinum toxin type A - produced by Clostridia Botulinum bacteria. | Fat transfer from one part of the body to another | Derived from purified bovine (cow) collagen | Derived from human collagen | Synthetic form of material found in bone and teeth |
| How it works? | Adds
volume | Temporarily relaxes the muscle | Adds volume | Adds volume | Adds volume | Adds volume |
| Injection Areas | Nasolabial folds, forehead wrinkles, smile lines and lips | Forehead, frown lines, crow's feet and vertical neck bands | Nasolabial folds, crow's feet, lips, frown lines, and facial recontouring | Nasolabial folds, crow's feet, frown lines, and lips | Nasolabial folds, frown lines, crow's feet, and lips | Nasolabial folds, frown lines, crow's feet, and lips |
| Results | 4 months to 1 year: depending on formulation | Up to 6 months | Highly variable: months to years | Up to 6 months | Up to 6 months | 2 years and
possibly longer |
| Average Cost | $542 | $387 per procedure | $1,300 per procedure | $389 per procedure | Unknown | $1,119 |
| United States Availability | Yes – FDA approved | Yes – FDA approved for frown lines; other uses are "off-label" | Yes – Does not require FDA approval | Yes – FDA approved | Yes – FDA approved | Yes - cosmetic use "off-lab" |
| Back to Work | No
downtime | No
downtime | Minor: 1-4 days Extensive: 7-14 days | No
downtime | No
downtime | No
downtime |
| Possible Reactions | Swelling, redness, and tenderness | Bruising, redness, droopy eyelid, flu-like symptoms, headache | Swelling, bruising and lumpiness | Slight bruising and allergic reactions | Swelling, redness and bruising | Swelling, redness, bruising, and lumpiness |
| What to consider? | Does not
require
allergy skin
test | None identified at this time | Requires a donor site (i.e., thighs, abdomen, or buttocks) | Requires allergy skin test–at least one month wait | Does not require allergy skin test | Does not require allergy skin test |
